Dr. Semiha Yenigün | Plant Biochemistry | Best Researcher Award
Post Doctor at Ondokuz Mayıs University | Turkey
Dr. Semiha Yenigün is an accomplished chemist specializing in antioxidant activity determination methods, enzyme inhibition studies, antimicrobial activity, molecular dynamics simulations, computational chemistry, pharmacokinetics, and natural product isolation, with a strong research focus on the bioactive compounds of medicinal plants, fungal endophytes, phytochemicals, and molecular modeling approaches integrating both in vitro and in silico methodologies. She completed her academic journey at Ondokuz Mayıs University, progressing through undergraduate, graduate, and doctoral training with outstanding academic performance, earning high honors and demonstrating remarkable expertise in chemical sciences. Her scientific contributions include extensive research on phytochemical profiling, DNA protection mechanisms, enzymatic kinetics, molecular docking, molecular dynamics, MM-PBSA, ADME/T predictions, PASS analysis, LC-ESI-MS/MS characterization, and the discovery of novel bioactive molecules from Nepeta species, Rosa species, Elaeagnus umbellata, Paliurus spina-christi, Atriplex nitens, Coriandrum sativum, Lactuca anatolica, Chenopodium quinoa, and other botanicals, reflecting her multidisciplinary command of natural products chemistry and computational biochemistry. As a co-author of numerous publications in high-impact journals covering antibacterial flavonoids, cytotoxic compounds, metabolic enzyme inhibitors, food additive potential molecules, silver nanoparticle green synthesis, and bioactivity-guided phytochemical isolation, she has significantly contributed to expanding knowledge in medicinal chemistry and chemical biology. She has actively participated in scientific congresses with presentations on enzyme inhibition, phytochemical composition, antioxidant profiles, and plant-derived bioactive substances. Her involvement in major national scientific research projects, particularly within Türkiye’s chemistry and biology research support programs, highlights her commitment to innovation and academic excellence. Through her continued work in experimental and computational chemistry, Semîha Yenigün stands out as a dynamic and productive researcher whose scholarship strengthens the intersection of natural product chemistry, molecular modeling, and biological activity evaluation.
Featured Publications :
Chi, G. F., Khan, S., Basar, Y., Kuete, J. R. N., Matieta, V. Y., Kuete, J. B. T., Megaptche, J. F., Chongong, M. A., Yenigun, S., Ayimele, G. A., et al. (2025). Antibacterial flavonoids from Tetrapleura tetraptera (Fabaceae) fruit pulp: In silico studies. South African Journal of Botany.
Nayel, N. H. N., Marah, S., Yenigun, S., Ozen, T., Yildiz, I., Erenler, R., & Behcet, L. (2025). Green-chemically synthesized silver nanoparticles using Lactuca anatolica leaf extract: Characterization, biological assessment, molecular docking study, and DFT calculation. Inorganic Chemistry Communications.
Başar, Y., Demirtaş, İ., Yenigün, S., İpek, Y., Özen, T., & Behçet, L. (2025). Molecular docking, molecular dynamics, MM/PBSA approaches and bioactivity studies of nepetanudoside B isolated from endemic Nepeta aristata. Journal of Biomolecular Structure and Dynamics.
Basar, Y., Yenigun, S., Ozen, T., Demirtas, I., Balpınar, O., & Behcet, L. (2025). Nepetanudoside B, a potential new food additive isolated from Nepeta aristata: Antioxidant, antibacterial, DFT, ADME/T, PASS prediction and MTT analysis studies. European Food Research and Technology.
Yakan, H., Muğlu, H., Bakır, T. K., Yenigün, S., Amhimmid, A. G. A. M., Çavuş, M. S., & Özen, T. (2025). New 5-iodoisatin-thiosemicarbazones: Preparation, spectroscopic characterization, antioxidant, urease inhibition activities, DFT studies, molecular docking, and molecular dynamic simulations. Research on Chemical Intermediates.