Trevor Penning | Plant Biochemistry | Best Researcher Award

Published on by Botany Scientist

Prof. Trevor Penning | Plant Biochemistry | Best Researcher Award

Professor at University of Pennsylvania | United States

Professor Trevor Penning, a distinguished biochemist, earned his B.Sc. with First Class Honors and Ph.D. in Biochemistry from the University of Southampton, UK. With a career spanning over four decades, he has served in leading academic and administrative roles at the University of Pennsylvania’s Perelman School of Medicine, including Director of the Center of Excellence in Environmental Toxicology and the Translational Research Training Program. His professional experience bridges pharmacology, biochemistry, and environmental health sciences, focusing on aldo-keto reductases (AKRs), hydroxysteroid dehydrogenases, and quinone metabolism. His research interests center on steroid biochemistry, endocrine disruptors, carcinogen activation, and the molecular mechanisms underlying redox biology and disease. Renowned for his scientific rigor, he possesses advanced research skills in enzymology, molecular pharmacology, toxicology, and translational biochemistry. Professor Penning’s prolific research output includes over 1,451 publications with 25,299 citations across 14,355 documents and an impressive h-index of 80, reflecting his global impact. His numerous awards and honors include the Founders Award from the American Chemical Society and the Molinoff Endowed Professorship. As Editor-in-Chief of Steroids and Fellow of the American Chemical Society, he continues to shape biochemical and toxicological research worldwide. His lifelong contributions exemplify excellence in scientific innovation, mentorship, and leadership in environmental and biochemical sciences.

Profile : Scopus | Google Scholar | ORCID

Featured Publications

Bolton, J. L., Trush, M. A., Penning, T. M., Dryhurst, G., & Monks, T. J. (2000). Role of quinones in toxicology. Chemical Research in Toxicology, 13(3), 135–160.

Stanbrough, M., Bubley, G. J., Ross, K., Golub, T. R., Rubin, M. A., Penning, T. M., et al. (2006). Increased expression of genes converting adrenal androgens to testosterone in androgen-independent prostate cancer. Cancer Research, 66(5), 2815–2825.

Tebay, L. E., Robertson, H., Durant, S. T., Vitale, S. R., Penning, T. M., et al. (2015). Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease. Free Radical Biology and Medicine, 88, 108–146.

Penning, T. M., Burczynski, M. E., Jez, J. M., Hung, C. F., Lin, H. K., Ma, H., Moore, M., et al. (2000). Human 3α-hydroxysteroid dehydrogenase isoforms (AKR1C1–AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the metabolism of androgens, estrogens, and bile acids. Biochemical Journal, 351(1), 67–77.

Jez, J. M., Bennett, M. J., Schlegel, B. P., Lewis, M., & Penning, T. M. (1997). Comparative anatomy of the aldo–keto reductase superfamily. Biochemical Journal, 326(3), 625–636.