Dr. Mebratu Teferi | Social Sciences | Best Researcher Award
Peking Union Medical College, China
Dr. Haiyan He is a Principal Investigator at the Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, China. She specializes in bioorganic chemistry, natural product biosynthesis, metabolic engineering, and biocatalysis. Her research focuses on engineering natural biosynthetic pathways and developing innovative approaches for natural product synthesis. Dr. He has contributed significantly to microbial biosynthesis and enzymatic engineering through high-impact publications in internationally reputed journals.
Professional Profile
Education
- Ph.D. in Bioorganic Chemistry
State Key Laboratory of Bioorganic and Natural Product Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (2007–2012).
- B.Sc. in Chemistry
Tianjin University (2003–2007).
Professional Experience
- Principal Investigator
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences (2021–Present).
- Research Associate
Department of Chemistry, The University of British Columbia (2019–2021).
- Postdoctoral Research Fellow
Department of Chemistry, The University of British Columbia (2014–2019).
- Research Associate
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (2012–2014).
Research Interest
Dr. Haiyan He’s research interests include:
- Engineering and redesign of natural biosynthetic pathways
- Combinatorial biosynthesis for natural products
- Protein-directed evolution and biocatalysis
- Metabolic engineering and microbial synthesis
- Natural product chemistry and enzymatic catalysis
Award and Honor
- Appointed as Principal Investigator at the prestigious Chinese Academy of Medical Sciences.
- Published research in globally recognized journals including Nature Chemistry, Journal of the American Chemical Society, Chemical Society Reviews, and Angewandte Chemie International Edition.
- Recognized for outstanding contributions to natural product biosynthesis, metabolic engineering, and synthetic biology.
Conclusion
Dr. Haiyan He is an accomplished scientist in the field of bioorganic chemistry and natural product biosynthesis. Through her pioneering work in metabolic engineering, enzymatic catalysis, and biosynthetic pathway redesign, she has established herself as a leading researcher with strong international collaborations and impactful scientific contributions. Her innovative studies continue to advance biotechnology and pharmaceutical sciences globally.
Publications Top Noted
- Synthetic and biosynthetic routes to nitrogen-nitrogen bonds – Chemical Society Reviews (2022).
- Glycine-derived Nitronates Bifurcate Between O-Methylation and Denitrification in Bacteria – Nature Chemistry (2021).
- Two-Enzyme Pathway Links L-Arginine to Nitric Oxide in N-Nitroso Biosynthesis – Journal of the American Chemical Society (2019).
- Cyclic natural product oligomers: diversity and (bio)synthesis of macrocycles – Chemical Society Reviews (2025).
- Nitramine Formation via a Cryptic Non-Ribosomal Peptide Synthetase-Dependent Strategy in N-Nitroglycine Biosynthesis – Angewandte Chemie International Edition (2025).